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Diagnostics World News | Funding for a diagnostic assay platform with superior sensitivity and specificity and a faster response time for detecting emerging pandemic situations, metabolomics diagnostic research, an infrared spectroscopy platform that detects the presence or absence of disease, and more.
Feb 21, 2023
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Diagnostics World News | Efforts to use digital endpoints to modernize clinical trials have been slowed by an assortment of challenges. But the field will be getting a big push in the right direction in another few months when the first hard evidence will be published demonstrating digital endpoints can live up to their promise of delivering smaller, speedier trials.
Feb 16, 2023
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Diagnostics World News | Researchers at Harvard University and Brigham and Women’s Hospital, along with collaborators from Bogazici University in Turkey, have revealed new technology intended to help make timely decisions during surgery. Their method uses artificial intelligence to enhance the image quality of frozen tissue samples in hopes of improving diagnostic speed and accuracy.
Feb 14, 2023
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Diagnostics World News | Researchers at Duke University have come up with the new “best-in-class” systemic biomarker predictive of clinically relevant knee osteoarthritis that significantly outperforms the top-rated urine test when it comes to recognizing disease progression. Development of the targeted multiple reaction monitoring proteomic panel has been a 12-year labor of love for the team.
Feb 9, 2023
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Diagnostics World News | Researchers in Germany have developed a series of innovative solutions for probing the body more broadly and deeply for early pathological signs of diseases ranging from metabolic disorders and neurodegenerative diseases to cancer. Their novel technology, dubbed DISCO-MS, does spatial proteomics in three-dimensional (3D) intact specimens using a combination of whole-organ and whole-organism clearing and imaging, deep-learning-based image analysis, robotic tissue extraction, and ultrahigh-sensitivity mass spectrometry.
Feb 8, 2023
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Diagnostics World News | Research scientists at Indiana University–Purdue University Indianapolis and Regenstrief Institute have developed a “passive digital marker” (PDM), powered by machine learning, to help identify people at risk for Alzheimer’s disease and related dementias at an earlier stage in primary care settings. Application of the PDM will now be tested in the real world in a pair of pragmatic randomized controlled trials.
Feb 7, 2023
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Diagnostics World News | Researchers at the Norwegian University of Science and Technology and the University of Notre Dame have developed a new microresonator for biochemical sensing. This is big news, according to Dingding Ren and David Burghoff, co-leaders in joint research between the two institutes.
Feb 2, 2023
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Diagnostics World News | An international team of neuroscientists expect to soon be handing off development of a promising new blood test for Alzheimer’s disease neurodegeneration to a U.S.-based biomarker company. The immunoassay selectively measures brain-derived tau and was recently demonstrated to outperform both assessments of plasma total tau levels and measurements of neurofilament light chain concentration, a protein marker of nerve cell damage.
Jan 31, 2023
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Diagnostics World News | A digital AI platform to enrich breast cancer grading and improve risk categorization; novel tests significantly reduce hospitalization costs and mortality and morbidity rates in newborns and premature infants; the first blood test superior to stool tests in detecting advanced adenomas and colorectal cancer; and more.
Jan 26, 2023
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Diagnostics World News | Funding for a decision-support platform to enhance surveillance, detection, and triage of neglected tropical diseases and other rare infectious diseases, transcriptome-wide profiling and advanced medicinal chemistry technology, novel pathology consulting, and more.
Jan 24, 2023
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Diagnostics World News | At the J.P. Morgan Healthcare Conference last week, several diagnostics companies offered insight into their directions and plans for the coming year, and oncology diagnostics was a refrain. Across the space, test developers and researcher groups are turning their attention first to minimal residual disease (MRD) tests. Here we gather feedback from a few of the companies that presented last week.
Jan 19, 2023
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Diagnostics World News | Scientists from the National University of Singapore (NUS) have discovered a blood test for monitoring cancer patients that could be done for as little as $35. The new Heatrich-BS assay sequences cell-free DNA in clinical samples that get heated to isolate cancer-specific signatures, according to Cheow Lih Feng, assistant professor at NUS’s Institute for Health Innovation & Technology and department of biomedical engineering.
Jan 18, 2023
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Diagnostics World News | A team of researchers is pursuing new technology to address racial disparities in blood measurements. The group ultimately hopes to develop a portable wearable device, like a monitor or watch, capable of accurately and non-invasively reading blood regardless of skin tone.
Jan 17, 2023
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Diagnostics World News | In a somewhat subdued presentation compared to years past, Illumina CEO Francis deSouza kicked off his annual J.P. Morgan Healthcare Conference talk highlighting the breadth of the genomics market. deSouza sees a $120 billion total addressable market for Illumina, with oncology testing representing more than half of the opportunity.
Jan 12, 2023
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Diagnostics World News | Laser diodes many times stronger than the brightness of light-emitting diodes found on the back of Apple Watches and Fitbits are enabling development of a photoacoustic skin patch capable of continuously monitoring the amount and location of hemoglobin in deep tissues. This opens the possibility of noninvasively detecting organ dysfunction, cerebral or gut hemorrhages, cancer, and COVID complications with the convenience of a wearable.
Jan 10, 2023
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Diagnostics World News | We spoke with various companies in the Diagnostics World community to gain insights and predictions for the coming year. They predicted faster and more precise diagnostic testing, enhanced whole genome screening, novel therapies that empower patients to direct their healthcare journey, and more advances in proteomics.
Jan 5, 2023
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Diagnostics World News | Since Withings founder Eric Carreel bought his company back from Nokia in 2018, the consumer electronics company has broadened its focus from nice-to-have smart health devices that support daily well-being to connected, medical-grade products whose health impacts are being scientifically validated. The latest addition to the arsenal is U-Scan, which can perform daily urinalysis with a smart device that sits inside any toilet bowl.
Jan 4, 2023
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Diagnostics World News | In a paper published late last year in Nature Communications, researchers from Penn Medicine and Intel Labs report on what they call the largest to-date global federated learning effort to develop an accurate and generalizable machine learning model for detecting glioblastoma borders. The work has important implications both clinically and as a model for future large, federated learning projects.
Jan 3, 2023
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Diagnostics World News | Diagnostics has changed in the past three years with the pandemic necessitating regulatory changes and demanding technical innovation. Some of this change has been directly COVID-related, but much was simply fueled by increased funding and attention to diagnostic problems. This year we watched the results of those changes filter through the industry and spur new thinking.
Dec 29, 2022
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Diagnostics World News | An artificial intelligence electrocardiogram algorithm designed to enable the early suspicion of cardiac amyloidosis; a first-of-its-kind wearable and wireless facial electromyography solution to assess subtle facial expressions and decipher emotional reactions; fluorescent dye singles out cancer cells under near-infrared light; and more.
Dec 27, 2022