-
Diagnostics World | Strand Therapeutics will advance their pipeline of STX-001, a programmable mRNA therapy that expresses the cytokine interleukin-12 (IL-12) directly from the tumor microenvironment; Jocasta Therapeutics plan to further develop a - Klotho, a protein therapeutic targeting cognitive decline in neurodegenerative diseases; and more.
Aug 27, 2025
-
Diagnostics World | Roche announced the US Food and Drug Administration (FDA) 510(k) clearance for the cobas Respiratory 4-flex; Dana-Farber Cancer Institute researchers have developed a blood test that could transform the diagnosis and monitoring of multiple myeloma; and more.
Aug 26, 2025
-
Diagnostics World | Earlier this month, Boston Children’s Hospital, Broad Clinical Labs, and Dana-Farber Cancer Institute announced the formation of a collaborative clinical research and testing initiative, Boston Research in Innovative Genomics for Hematologic and Tumor Sequencing (BrightSeq).
Aug 21, 2025
-
Diagnostics World | Efforts to couple patient-level data with machine learning (ML) are going to accelerate “100-plus-fold” over the next decade, dramatically improving evidence-based decision-making and demonstrably improving patient care. In the diagnostics field, supervised learning that leverages classification represents the bulk of this work currently and may even suggest the algorithms best suited to the task at hand.
Aug 20, 2025
-
Diagnostics World | Ultima Genomics published updates on the single-nucleotide variant (SNV) detection capabilities of its ppmSeq technology and demonstrated ctDNA detection limits for ppmSeq, which extend beyond the limits of currently available minimal residual disease assays.
Aug 19, 2025
-
Diagnostics World | With the advent of large language models (LLMs), expert human abstractors are meeting their match when it comes to accurately identifying cancer progression events from electronic health records (EHRs). That’s one of the big surprises emerging from a study presented by Aaron Cohen, M.D., a practicing oncologist and head of oncology research at Flatiron Health, at a recent artificial intelligence and machine learning conference of the American Association for Cancer Research.
Aug 14, 2025
-
Diagnostics World | Like a smartphone housing many software applications, a multi-purpose platform looks to be the launchpad for a potentially huge number of medical devices. The Openwater system, under development for nearly a decade, holds promise in noninvasively diagnosing and treating disease using infrared light and low-intensity focused ultrasound (LIFU).
Aug 12, 2025
-
Diagnostics World | Researchers at Johns Hopkins University have developed Multimodal Artificial intelligence for ventricular Arrhythmia Risk Stratification (MAARS), a deep learning approach to predict lethal arrhythmia in patients with HCM by analyzing multimodal medical data.
Aug 7, 2025
-
Diagnostics World | The Alzheimer's Association International Conference was held last week in Toronto and researchers and companies gathered to present their progress in the fight to diagnose and treat Alzheimer’s disease. Among the timely new developments: new products from Quanterix; pre-clinical data from AltPep, OncoC4, and NKGen Biotech; pipeline updates from Eisai, Biogen, and Roche; and more.
Aug 6, 2025
-
Diagnostics World | Researchers at Virginia Commonwealth University have developed an artificial intelligence tool that could revolutionize cancer diagnostics by rapidly identifying distinct cell types in tissue biopsies, potentially transforming how clinicians make treatment decisions and predict patient responses to therapy.
Aug 5, 2025
-
Diagnostics World | UK Biobank completed the world’s largest whole body imaging project; Longhorn Vaccines and Diagnostics announced a strategic co-marketing agreement with Promega Corporation; and more.
Jul 31, 2025
-
Diagnostics World | Aqutal’s advance toward a therapy response prediction test in rheumatoid arthritis; Illimis Therapeutics plans to accelerate the development of GAIA-based Alzheimer's disease therapeutics and various immune disorders; and more.
Jul 30, 2025
-
Diagnostics World | A surge in research and development around fluorophores, various types of glowing molecules used to enhance visualization during surgical procedures, is driving excitement about their potential to improve the performance of human surgeons and “pave the way” for even better autonomous robotic surgery.
Jul 24, 2025
-
Diagnostics World | Two of the great promises of AI is that it can help fill the gap in care in underserved communities and that it will give clinicians in high-demand specialties tools to meet that demand. One panel of experts at the HIMSS AI in Healthcare Forum in Brooklyn, NY, July 11-12, described how their organizations are implementing projects in exactly those areas. The HIMSS AI in Healthcare Forum brought together IT leaders, clinicians, and administrators to discuss how AI is being implemented in healthcare systems across the country.
Jul 23, 2025
-
Diagnostics World | In a proof-of-concept study, a platform integrating nanomedicine with artificial intelligence (AI) and “actual causality” analysis succeeded in pinpointing a pair of proteins thought to play key roles in the development of metastatic prostate cancer and atherosclerosis. The technology is the basis of a biotech company launching today that will use the same approach to identify potential biomarkers and drugs for treating a wide range of catastrophic diseases, including cardiovascular and neurodegenerative diseases as well as different types of cancers.
Jul 22, 2025
-
Diagnostics World | Swiss researchers have achieved a significant breakthrough in cancer diagnostics, demonstrating that advanced multiomics testing can successfully predict the most effective treatments for melanoma patients within four weeks—a timeline fast enough for real-world clinical use.
Jul 18, 2025
-
Diagnostics World | A study has revealed that phosphorylated tau (p-tau217), a key biomarker for Alzheimer's disease diagnosis, appears at even higher levels in healthy newborns than in adults with Alzheimer's disease—a finding that could reshape how clinicians interpret this widely-used diagnostic tool.
Jul 17, 2025
-
Diagnostics World | A growing number of promising young companies are developing tests that are particularly good at picking up early cancer, initially for a single type of cancer but with the potential to eventually be extended to multiple cancer types. A handful of these startups will be spotlighted at the upcoming Next Generation Dx Summit .
Jul 10, 2025
-
Diagnostics World | Molecular testing for minimal residual disease (MRD) is increasingly being used to detect cancer recurrence, and to that end many companies are actively developing assays. The tumor-informed approach based on the genetic mutations of patients has been particularly popular and often employs cell-free DNA (cfDNA) and more specifically circulating tumor DNA (ctDNA) analysis.
Jul 9, 2025
-
Diagnostics World | Researchers at the University of Chicago have published a new approach to cancer detection offering early unprecedented accuracy in identifying both early and late-stage cancers through a simple blood plasma test. The results were published today in a Brief Communication in Nature Biotechnology
Jul 8, 2025