Latest News

  • New Cloud-Native Database Offers Rapid Diagnosis of Rare Childhood Genetic Disease

    Diagnostics World News | Stephen Kingsmore, Rady Children’s Institute for Genomic Medicine, and Stavros Papadopoulos, TileDB, presented at Bio-IT World Conference & Expo about diagnostic whole-genome testing, newborn screening, treatment integration, and a single-platform multi-dimensional database.

    May 18, 2022
  • Microchip With At-Home Diagnostic Potential

    Diagnostics World News| A first-of-its-kind microfluidic diagnostic device that eliminates the usual liquid handling steps could enable pathogen detection, as well as gene sequencing, outside of a lab setting involving a lot of equipment and personnel. The small, no-frills chip is being developed by electrical and computer engineers at the University of Minnesota Twin Cities.

    May 17, 2022
  • Sequencing-Based Initiative Now Exploring How Best To Return The Findings

    Diagnostics World | A pioneering program of Geisinger Health System has returned clinically actionable results from exome sequencing to a record-breaking 3,400 individuals at increased risk for potentially life-threatening conditions such as hereditary breast and colon cancers, familial hypercholesterolemia (FH), and heart disease. The MyCode Community Health Initiative, enabled by a 2014 agreement with Regeneron Pharmaceuticals, draws from participants in a sizable DNA biobank who agree to the sequencing and results reporting.

    May 11, 2022
  • Headway On Next-Gen Skin Gas Sensing For Metabolic Diseases

    Diagnostics World News | An interdisciplinary team of researchers at The Ohio State University (OSU) is creating a “new paradigm for personalized medicine” with a skin gas sensing device for monitoring metabolism and managing weight.

    May 5, 2022
  • The Case For Preemptive, Sequence-Based Pharmacogenomics Testing

    Diagnostics World News | Over the next few years, pharmacogenomics could start to become a standard component of clinical care to improve drug efficacy and avoid adverse responses when certain medicines are prescribed.

    May 3, 2022
  • Follow the Money: AI-Powered Disease Detection, Non-Invasive Brain Imaging, More

    Diagnostics World | Funding for AI in disease detection and non-invasive brain diagnostics, immune-oncology cancer therapeutics, tissue therapeutics, and more.

    Apr 29, 2022
  • Covid Diagnostics, Pre-Term Birth Prediction, High-Plex Spatial Imaging Diagnostics; More

    Diagnostics World News | New genomics efforts in Brazil, HPV variant tests, COVID-19 virus and antibody tests, pre-term birth prediction by RNA profiling, metabolomics-based diagnostics, high-plex spatial imaging, blood-based glycoproteomics, new device for detecting mild cognitive impairment, and an award for rapid infection diagnostics.

    Apr 28, 2022
  • New DNA Test Easily Diagnoses Difficult-To-Detect Mutations

    Diagnostics World | Researchers in Australia played a leading role in development of a DNA-based test to catch what short-read Illumina sequencing often misses: long and repetitive genetic variants implicated in about 40 late-onset neurodegenerative and neuromuscular conditions. These highly complex short tandem repeat (STR) expansion disorders, which have proven difficult to profile with any technology, can now be handily diagnosed with Oxford Nanopore Technology (ONT).

    Apr 26, 2022
  • A COVID Diagnostics Reset: Making Accurate Diagnostics More Accessible

    Diagnostics World | At the height of the Omicron surge this winter, at-home rapid tests and PCR testing were hard to come by for everyone, but especially people with low-incomes, non-native English speakers, and immigrant communities. Along with more eligible people being vaccinated, an affordable, accessible NAAT test for the masses is the most effective way to live with the virus rather than being dominated by it again.

    Apr 22, 2022
  • Stanford: ‘Clinical Grade’ Long-Read Genome Sequencing Is Here

    Diagnostics World | A Stanford team led by Euan Ashley, professor of medicine, genetics and biomedical data science, sequenced a patient’s genome in a snappy five hours and two minutes on a PromethION platform from Oxford Nanopore, an achievement ratified by the Genome in a Bottle Consortium of the National Institute of Science and Technology.

    Apr 20, 2022
  • CLIA-Certified Alzheimer’s Blood Test Gets High Marks In Global Study

    Diagnostics World | A blood test to help clinicians diagnose Alzheimer’s disease is “on the road” to effectively replacing cerebrospinal fluid (CSF) testing and PET scans for detecting Alzheimer’s pathology, according to Randall J. Bateman, M.D., a professor of neurology at Washington University School of Medicine and co-developer of the plasma protein assay. A commercial version of the test, PrecivityAD, is already being used extensively in clinical trials as well to evaluate patients in real-world settings.

    Apr 19, 2022
  • Inactive Coagulation Proteins Could Be Key To Early Detection Of Sepsis

    Diagnostics World News | Coagulation factor proteins in the blood might be incorporated into standard blood tests to rapidly detect sepsis soon after infection but before disease symptoms such as excessive inflammation and blood clotting have happened, suggests a research initiative that markedly increased the survival of mice.

    Apr 14, 2022
  • EMA Endorses Biomarkers For Type 1 Diabetes Prevention Trials

    Diagnostics World | Following many years of collaborative patient-level data sharing across stakeholder groups, the European Medicines Agency (EMA) recently endorsed pancreatic islet autoantibodies as enrichment biomarkers for type 1 diabetes (T1D) trials focused on delaying or preventing the disease. The Qualification Opinion appears on both the EMA website and that of the Critical Path Institute’s (C-Path) Type 1 Diabetes Consortium (T1DC).

    Apr 11, 2022
  • The Relevance of Glycoproteomics to Diagnostics and Clinical Management

    Diagnostics World | For many clinicians, glycoproteomics is a new and unfamiliar field. However, this emerging “omic” has demonstrated potential to identify novel biomarkers and advance the field of diagnostics. Formerly confined to the research laboratory, the once daunting study of glycoproteomics (or “when sugar meet protein”) has been transformed by the use of machine learning.

    Apr 8, 2022
  • Mayo Experts Say The Voice Could Offer Measurable Signals Of Heart Health

    Diagnostics World News | Scientists at the Mayo Clinic are applying artificial intelligence (AI) to pick up auditory signals of heart health undetectable by the human ear, notably subtle acoustic changes that might not be intuitive or formally taught in medical school or during residency and fellowship training. Their vocal biomarker is based on the supposition that cardiovascular disease is likely expressed throughout the body at large, including the phonatory system.

    Apr 7, 2022
  • Pan-Cancer Testing: A Closer Look at Different Technology Approaches

    Diagnostics World | Researchers are currently exploring various approaches to pan-cancer testing, including the measurement of changes in DNA or RNA sequences, patterns of DNA methylation or fragmentation, levels of protein biomarkers, and antibodies, among others. For now, it remains to be seen which of these differing routes will lead to the most effective method or methods.

    Apr 5, 2022
  • Follow the Money: Synthetic Antibodies, PCR-Based In-Home Medical Diagnostics, Novel Cell Assay Platform

    Diagnostics World | Funding for PCR-based in-home medical diagnostics, microcarriers for cell-based assays, higher-order protein structural analysis, 3D genomics, AI-powered single-cell analysis, and more.

    Mar 31, 2022
  • Pathology Image Digitization and AI Analysis, New Proteomics Solutions, Improved Diagnostics for Drug Efficacy, AEs

    Diagnostics World News | A genomic network model is used to identify aurora kinase inhibitor-sensitive lung tumors, AI seeks to improved prostate cancer diagnosis and prognosis, improved liver cancer detection is achieved with simple blood test, immunohistochemistry analysis standardization, and PacBio and Sick Kids in Toronto are working to identify genetic variants responsible for childhood disease using HiFi WGS.

    Mar 30, 2022
  • Teeny ‘Falloposcope’ Hunts For Early Signs Of Cancer

    Diagnostics World News | Biology and technology have finally advanced to the point where a teentsy device for imaging the inside of the fallopian tubes is recognized both as an unmet clinical need and a plausible engineering feat. Introducing the falloposcope, intended to search for signs of early-stage ovarian cancer and currently undergoing pilot testing in volunteers having their tubes removed for reasons other than cancer to establish a baseline for normal.

    Mar 29, 2022
  • How The Diagnostic Community Can Integrate AI Into AMR

    Diagnostics World News | As the global COVID-19 battle wages on, the ‘silent pandemic’ of antimicrobial resistance (AMR) continues to expand around the world. As the medical community continues to evaluate new technology-based approaches to fight AMR, microbial genome sequencing coupled with artificial intelligence (AI) are among the first topics brought up for discussion, and many laboratories are already embracing these new technologies.

    Mar 25, 2022