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Diagnostics World | A global collaborative of researchers has used a novel platform based on cell-free RNA (cfRNA) to monitor patterns of gene expression as pregnancy progresses—including, surprisingly, genes that appear to originate with the developing fetus. They recently demonstrated the platform’s potential as a pregnancy screening tool, using preeclampsia as a test case, but it might logically also be brought to bear in the future treatment and prevention of any number of pregnancy-related complications.
Jan 5, 2022
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Diagnostics World | Researchers in China have developed a noninvasive skin cholesterol detection system that could be useful in the long-term lipid management of cardiovascular diseases, meeting a critical unmet need.
Jan 4, 2022
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Diagnostics World News | Technologies for blood collection and testing, immune-competent organoids, flow cytometry for cell therapies, and SPR-based proteomics
Dec 28, 2021
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Diagnostics World News | With vaccines becoming widely available, there was still a need to expand testing capabilities, bringing these efforts right into the home with over-the-counter tests and thinking outside of the box with cheap smell-based testing. We also learned more about the process for various tests and interventions to transition from EUA to full approval, or why they might be abandoned.
Dec 27, 2021
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Diagnostics World | Diagnostics partnerships on scalp-sensing electrodes, AI-powered pathology, and devices in China. Plus new products from Leica Microsystems, Foundation Medicine, PerkinElmer, more.
Dec 22, 2021
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Diagnostics World News | People with type 1 diabetes face unique challenges in managing their disease, including, for many decades, the need to review their blood sugar levels and adjust insulin dosing by hand. Creation of an artificial pancreas system connecting glucose sensors and insulin pumps introduced automation, the technology has not been routinely available. Online peer communities filled this gap by engineering sophisticated, do-it-yourself solutions.
Dec 21, 2021
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Bio-IT World | A growing number of companies are endeavoring to replicate the success of gene sequencing juggernaut Illumina in the burgeoning field of proteomics. A top contender is Nautilus Biotechnology, which has spent the past few years drumming up excitement about the potential for comprehensively profiled proteins to make therapeutic and diagnostic development more effective and time efficient.
Dec 16, 2021
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Diagnostics World News | Histopathology is destined to go through the same sort of digital transformation that occurred in the home entertainment industry with the wholesale switchover from in-person visits at Blockbuster stores to anytime movie availability from streaming service Netflix.
Dec 14, 2021
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Diagnostics World | A group of cell engineers and synthetic biologists at Harvard University and Massachusetts Institute of Technology (MIT) has developed a tech tool called “eToeholds” that could help improve the safety and efficacy of RNA and cell therapies, in addition to enabling new forms of detection.
Dec 9, 2021
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Diagnostics World News | At Oxford Nanopore’s virtual Community Meeting last week, CTO Clive Brown presented new sequencing chemistries and hardware to enable liquid biopsy in the field.
Dec 6, 2021
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Diagnostics World News | American Rescue Plan investment for diagnostics manufacturing, point-of-care gynecological imaging, skincare diagnostics, sepsis diagnostics for warfighters, and more.
Dec 2, 2021
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Diagnostics World News | French AI startup Owkin announces big funding and Memorial Sloan Kettering Cancer Center partnership, Roche and Genentech choose Flywheel cloud informatics, and Talis Biomedical gets FDA EUA for COVID-19 test. Plus new products from VIDA Diagnostics, Oncocyte, Metabolon and more.
Nov 30, 2021
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Diagnostics World | Illumina and Genetic Alliance announced this week the creation of the iHope Genetic Health program aimed at providing whole-genome sequencing access (WGS) to tens of thousands of patients across the globe impacted by genetic disease. At least half of iHope Genetic Health's efforts will be focused on areas of the world in need outside the US, with more than one-third of Illumina's support being dedicated to patients in Africa.
Nov 22, 2021
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Diagnostics World News | Labs around the country with next-generation sequencing capabilities have begun using a respiratory virus panel that simultaneously tests for SARS-CoV-2 and 40 other potentially co-occurring respiratory viruses, including four cold-causing coronaviruses, both types of respiratory syncytial viruses (RSV), and more than a dozen influenza viruses.
Nov 17, 2021
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Diagnostics World News| Geisinger researchers have been awarded a $5 million grant to develop a diagnostic tool for genetic disorders. With support from the National Institutes of Health’s National Human Genome Research Institute, the group plans to build a High Impact Phenotype Identification System. The aim is to trim the time between symptom onset and the discovery of a genetic basis to improve patient care and outcomes.
Nov 15, 2021
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Diagnostics World News | Researchers in Germany are developing a lateral flow assay that aims to inform people if they are at heightened risk of developing Alzheimer’s disease (AD) and the robustness of their “cognitive reserve” to stave off symptoms of degenerative brain changes—all by measuring levels of three microRNAs (miRNAs) circulating in their blood.
Nov 12, 2021
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Diagnostics World News | The U.K. 100,000 Genomes Project published the results of a pilot study seeking diagnoses for 4,660 participants from 2,183 families with rare diseases. They found that whole genome sequencing measurably improved diagnoses for patients with a wide range of genetic illnesses and saved money for the healthcare system.
Nov 11, 2021
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Diagnostics World News | Rising incidence of takotsubo or “broken heart” syndrome is highlighting the need to better differentiate the condition from myocardial infarctions involving blocked arteries as well as other types of myocardial infarction with non-obstructive coronary arteries (MINOCA)—and to figure out the root causes. The best that can be done for patients currently is to as quickly as possible get detailed pictures of their heart from cardiac magnetic resonance (CMR) imaging to improve the odds that they’ll be properly diagnosed and treated.
Nov 10, 2021
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Diagnostics World News | Researchers in Denmark are pursuing development of a diagnostic approach pairing a liquid biopsy test with nanoparticle tracking analysis to measure disease severity in patients with autoimmune diseases. While at least five years away from making an appearance in hospital labs, their patented Nanoscale Immunoactive Protein Quantification (NIP-Q) technique has already been used to discover patients with systemic lupus erythematosus (SLE) have a higher concentration of certain DNA–protein complexes in their blood.
Nov 4, 2021
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Diagnostics World News | In a new article published in JAMA Health Forum last week, members of the Association for Molecular Pathology COVID Response Steering Committee offered recommendations to improve the US’s ability to respond to the current COVID-19 pandemic and prepare for future emerging infectious disease outbreaks.
Nov 3, 2021